Types of insurance necessary to provide coverage to start up operations is driven primarily by business type. On a basic level, commercial operations will need a general liability policy; if there is an auto risk, depending on the type you will need either a standalone policy or to add a Hired Non-Owned endorsement to your general liability policy.
If an operation has any employees, workers compensation is mandated by most states. An operation may need workers compensation insurance even if the owner is the only employee, depending on the state of operations. If professional services are provided, either a standalone, or professional liability endorsement to a general liability policy may be desirable.